Kratom Beverages:
A Highly Attractive but Challenging Target
Beverages can be a great way to consume therapeutic bioactives. Making fast-acting, effective and pleasant-tasting functional beverages with kratom, however, has been a challenge until now. The solubility of mitragynine in neutral-pH and alkaline water is too low (0.0187 mg/ml at pH 9) )[1]. In acidic water, the solubility is higher (3.5 mg/ml at pH 4), however, mitragynine becomes unstable (10 % loss in 6 hours) )[1], so low-pH beverages have an extremely short shelf life.
Several vendors offer concentrated liquid kratom products (shots) with claims of improved mitragynine solubility, however, those products are based on solvents (mainly propylene glycol—the base ingredient of antifreeze) rather than water and tend to be extremely unpleasant (and unhealthy) to consume.
Kratom Therapeutic Benefits
Kratom (Mitragyna speciosa) is a tree of the coffee family native to Southeast Asia. Its leaves contain over 50 alkaloids, two of which—mitragynine and 7-hydroxymitragynine [2]—research shows they can produce stimulant effect at low/medium doses and act as a sedative at high doses [3].
A typical amount of mitragynine in a single kratom-based product serving is around 50 mg, with which most users report increased energy and focus (great for competitive sports or general workout), improved work capacity and alertness, heightened sociability, and enhanced libido. At higher doses, kratom has been reported to reduce anxiety and pain, alleviate fatigue and depression, and effectively treat opioid and alcohol withdrawal symptoms [3]. Discover the numerous potential benefits of Nanokinetics® kratom formulations, leveraging the premium quality and efficacy made possible by converting it into a water-soluble form.
Kratom Serving Amounts
Dry kratom leaves typically contain 1 – 1.5 % of mitragynine and an effectively negligible amount of 7-hydroxymitragynine. A common 50 mg mitragynine dose (adjusted up or down, depending on tolerance) corresponds to 3 – 5 g of the leaves, usually consumed by swallowing several capsules or tablets containing the dry leaf powder [4]. Kratom leaves can also be chewed or brewed, however, these consumption methods lead to unpredictable dosing and are unpleasant to most users due to kratom’s bitter and earthy taste.
Alternatively, kratom alkaloids can be extracted from the leaves, resulting in much more potent products. Unfortunately, since most extraction methods involve toxic organic solvents such as methanol, petroleum ether, hexane, chloroform, and methylene chloride [5], product contamination with residual solvents is common. Ready to explore safer and more effective kratom solutions? Contact the Nanokinetics team today to discover how our advanced extraction methods can transform your products.
WARNING!!
Prolonged daily kratom use may lead to dependence. Do not consume simultaneously with other drugs to avoid the possibility of serious side effects.
Welcome to Our Food-Grade-Extracted
Highly Water-Soluble Kratom
Achieve Rapid Solubility in Water or Any Other Beverage with Nanokinetics®
Our technology allows us to formulate mitragynine as a highly water-soluble powder, preserving its structure and functionality. This innovation enables us to produce effervescent kratom extract tablets that dissolve rapidly and completely in water (to full transparency and regardless of pH) or any other beverage and allow mitragynine to remain stable in any environment (before and after dissolution). Explore a range of product possibilities, including water-soluble kratom powder sachets, ready-to-brew items (tea, ground coffee, mate), infused instant powders (protein blends, instant coffee), and energy shots.
We would love to work with you and your brand!
Discover Nanokinetics®' meticulously crafted water-soluble ingredient solutions, spanning premium kratom formulations, water-soluble THC, CBD, kava, CoQ10, mushroom extracts, and many more. Tailored to meet your specific requirements, our products are available in small quantities for testing and R&D as well as in bulk. Reach out to the Nanokinetics® team for pricing and further information.
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